The Journal of
Clinical Psychiatry

Volume 82 • 2021 • 3

Meta-Analysis

Marine Omega-3 Fatty Acid Supplementation for Borderline Personality Disorder: A Meta-Analysis

J Clin Psychiatry 2021;82(3):20r13613

Roel J. T. Mocking, MD, PhD^a,b; Theo Ingenhoven, MD, PhD^b; Dominika M. Karaszewska, BSc^a

Meta-Analysis

Meta-Analysis of the Treatment of Posttraumatic Stress Disorder in Adults With Comorbid Severe Mental Illness

J Clin Psychiatry 2021;82(3):20r13584

Anouk L. Grubaugh, PhD^a; Wilson J. Brown, PhD^b; Jessica A. Wojtalik, PhD^c; Ursula S. Myers, PhD^a; Shaun M. Eack, PhD^d

Systematic Review

A Systematic Review of Complex Polypharmacy in Bipolar Disorder: Prevalence, Clinical Features, Adherence, and Preliminary Recommendations for Practitioners

J Clin Psychiatry 2021;82(3):20r13263

Joseph F. Goldberg, MD^b; Anna M. Kim, MD^a; Lisa Salstein, MD^b

Original Research

Trends in Medication Prescribing in Patients With PTSD From 2009 to 2018: A National Veterans Administration Study

J Clin Psychiatry 2021;82(3):20m13522

Beth E. Cohen, MD, MAS^a,f; Thomas C. Neylan, MD^a,b,c,e; Shira Maguen, PhD^a,b,c; Karen H. Seal, MD, MPH^a,c,f; Ilse Wiechers, MD^c,i,j; Nicholas Holder, PhD^a,b,c,*; Anne Woods, MS^d; Nancy Bernardy, PhD^g,h; Annie Ryder, BA^a,f; Ana-Marie Urbieta, MSW^a

Original Research

Insomnia, Suicidal Ideation, and Suicide Attempts in the Clinical Antipsychotic Trials of Intervention Effectiveness

J Clin Psychiatry 2021;82(3):20m13338

Joseph P. McEvoy, MD^a; Brian J. Miller, MD, PhD, MPH^a,*; William V. McCall, MD, MS^a

Original Research

Obsessive-Compulsive Disorder and Dementia Risk: A Nationwide Longitudinal Study

J Clin Psychiatry 2021;82(3):20m13644

Tung-Ping Su, MD^a,b,c; Mu-Hong Chen, MD, PhD^a,b; Cheng-Ta Li, MD, PhD^a,b; Wei-Chen Lin, MD^a,b; Shih-Jen Tsai, MD^a,b; Tzeng-Ji Chen, MD, PhD^d,e; Ya-Mei Bai, MD, PhD^a,b; Chih-Ming Cheng, MD^a,b; Chia-Fen Tsai, MD^a,b

Original Research

Divorce or Separation Following Postpartum Psychiatric Episodes: A Population-Based Cohort Study

J Clin Psychiatry 2021;82(3):20m13555

Trine Munk-Olsen, PhD^a; Benedicte M. W. Johannsen, MD^a; Merete L. Mægbæk, MSc^a; Bodil H. Bech, PhD^b; Thomas M. Laursen, PhD^a,c

Original Research

Cross-Sectional Associations Among Symptoms of Pain, Irritability, and Depression and How These Symptoms Relate to Social Functioning and Quality of Life: Findings From the EMBARC and STRIDE Studies and the VitalSign6 Project

J Clin Psychiatry 2021;82(3):20m13740

Madhukar H. Trivedi, MD^b; Manish K. Jha, MBBS^a,b; Taryn L. Mayes, MS^b; Alan Schatzberg, MD^c; Abu Minhajuddin, PhD^b,d; Cherise Chin Fatt, PhD^b

Original Research

Antipsychotic Use and Bloodstream Infections Among Adult Patients With Chronic Obstructive Pulmonary Disease: A Cohort Study

J Clin Psychiatry 2021;82(3):20m13516

Augusto Ferraris, MD^a,b; Alejandro G. Szmulewicz, MD, MPH^f; Federico Angriman, MD, MPH^d,e; Belén Blasco, MD^c; Nicolás Tentoni, MD^a,b; Facundo Del Olmo, MD^a; Tomás Barrera, MD^b

Original Research

Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder

J Clin Psychiatry 2021;82(3):20m13576

M. Katherine Shear, MD^e; Sidney Zisook, MD^f; Charles F. Reynolds III, MD^g; Naomi M. Simon, MD, MSc^a; Barry D. Lebowitz, PhD^f; Eric Bui, MD, PhD^c; Donald J. Robinaugh, PhD^c; Christine Mauro, PhD^d; Natalia A. Skritskaya, PhD^e; Peter J. Na, MD, MPH^a; Samrachana Adhikari, PhD^b; Kristin L. Szuhany, PhD^a; Alan Z. Chen, MSc^b; Rebecca R. Suzuki, BA^a; Matteo Malgaroli, PhD^a

Original Research

Transdiagnostic Psychiatric Symptoms, Burnout, and Functioning in Frontline Health Care Workers Responding to the COVID-19 Pandemic: A Symptomics Analysis

J Clin Psychiatry 2021;82(3):20m13766

Robert H. Pietrzak, PhD, MPH^a,b,c,j; James W. Murrough, MD, PhD^d,e; Steven M. Southwick, MD^a,c; Dennis Charney, MD^c,d,g; Lorig K. Kachadourian, PhD^a,b,*; Adriana Feder, MD^c; Jordyn H. Feingold, MAPP^f; Lauren Peccoralo, MD^f,h,I; Jonathan Ripp, MD, MPH^h,I; Halley Kaye-Kauderer, BA^f

Original Research

Frailty as a Predictor of Mortality in Late-Life Depression: A Prospective Clinical Cohort Study

J Clin Psychiatry 2021;82(3):20m13277

Ivan Aprahamian, MD, PhD^h; Hannie C. Comijs, PhD^g; Richard C. Oude Voshaar, MD, PhD^a; Radboud M. Marijnissen, MD, PhD^a,e; Matheus H. L. Arts, MD, PhD, MSc^a,b,c; Karen S. van den Berg, MD, MSc^a,d; Linda de Jonge, PhD^b; Annette J. M. Hegeman, MD, PhD^d; Rose M. Collard, PhD^f; Paul Naarding, MD, PhDⁱ

Original Research

Impact of the COVID-19 Pandemic on Child and Adolescent Psychiatric Emergencies

J Clin Psychiatry 2021;82(3):20m13467

Benedetto Vitiello, MD^a; Chiara Davico, MD^a,‡,*; Daniele Marcotulli, MD, PhD^a,‡; Caterina Lux, MD^a; Dario Calderoni, MD^b; Luca Cammisa, MD^b; Claudia Bondone, MD^c; Martina Rosa-Brusin, MD^a; Ilaria Secci, MD^a; Marzia Porro, MD^a; Roberta Campanile, MD^d; Chiara Bosia, MD^a; Federica Di Santo, MD^b; Arianna Terrinoni, MD^b; Federica Ricci, MD^a; Federico Amianto, MD, PhD^e; Antonio Urbino, MD^c; Mauro Ferrara, MD^b

Original Research

Persons With Debt Burden Are More Likely to Report Suicide Attempt Than Those Without: A National Study of US Adults

J Clin Psychiatry 2021;82(3):19m13184

Diana E. Naranjo, MPH^a,c; Joseph E. Glass, MSW, PhD^b; Emily C. Williams, MPH, PhD^a,b,c

Original Research

Therapeutic Response Is Associated With Antipsychotic-Induced Weight Gain in Drug-Naive First-Episode Patients With Schizophrenia: An 8-Week Prospective Study

J Clin Psychiatry 2021;82(3):20m13469

Xiang Yang Zhang, PhD, MD^e,*; Mei Hong Xiu, PhD^d,*; Ying Qi Chen, MD, PhD^a,‡; Xi Rong Li, MD^b,‡; Lie Zhang, MD^c; Wei Bo Zhu, MD^c; Ya Qing Wu, MD^c; Xiao Ni Guan, MD^a

Academic Highlights

Addressing Patients’ Unmet Needs to Improve Outcomes in Schizophrenia

J Clin Psychiatry. 2021;82(3):IC20018AH3C

John M. Kane, MD^b; Philip D. Harvey, PhD^a

Perspective

The Epigenetic Connection to Black Disparity

J Clin Psychiatry 2021;82(3):21com13858

Robert M. Post, MD

Clinical and Practical Psychopharmacology

β-Blockers and the Risk of New-Onset Depression: Meta-analysis Reassures, but the Jury Is Still Out

J Clin Psychiatry 2021;82(3):21f14095

Chittaranjan Andrade, MD

Clinical and Practical Psychopharmacology

Fluoxetine for Stroke: A Mixed Bag of Outcomes

J Clin Psychiatry 2021;82(3):21f14106

Chittaranjan Andrade, MD

ASCP Corner

Therapeutic Potential of Psychedelics in Treatment of Psychiatric Disorders, Part 2: Review of the Evidence

J Clin Psychiatry. 2021;82(3):20ac13787

Rajiv Radhakrishnan, MBBS, MD^e; Avinash Hosanagar, MD^a,b; Joseph Cusimano, PharmD^c,d

Case Report

A Change in Blood Carbamazepine Levels Associated With Cannabis Use: Implications for Clinical Practice

J Clin Psychiatry 2021;82(3):20cr13777

Kathryn K. Ridout, MD, PhD^a,b; Samuel J. Ridout, MD, PhD^a; Kelly C. Young-Wolff, PhD, MPH^b

Letter to the Editor

Posttraumatic Stress Disorder Symptom Severity Does Not Predict Depression Improvement, but May Impact Clinical Response and Remission

J Clin Psychiatry 2021;82(3):20l13751

Noah S. Philip, MD^a,b; Sydney Brigido, BA^a,b; Melanie Bozzay, PhD^a,b

Letter to the Editor

Veterans With Comorbid Depression and PTSD Can Be Effectively Treated With TMS

J Clin Psychiatry 2021;82(3):20l13751a

F. Andrew Kozel, MD, MSCR^f; Michael J. Hernandez, MD^a,b; Tea Reljic, MS, MPH^c; Kimberly Van Trees, RN^d; Sean Phillips, MD^a,b; Jaffrey Hashimie, MD^a,b; Laura Bajor, DO^a,b; Jennifer Yehl, MD^a,b; Barbara C. McKenzie, MA^e; Christine Burke, RN^d; Gregory A. Sullivan, MD^a,b; Ambuj Kumar, MD, MPH^c; Deborah L. Sanchez, MD, MPH^a,b; Glenn Catalano, MD^a,b

Letter to the Editor

It Is Too Early to Put Delirium Prophylaxis to Bed: Stronger Evidence Is Needed for Suvorexant

J Clin Psychiatry. 2021;82(3):20lr13818.

John O. Brooks III, PhD, MD^a,*; Jennifer L. Kruse, MD^a

Letter to the Editor

Studies Support the Use of Suvorexant for the Prevention of Delirium

J Clin Psychiatry 2021;82(3):20lr13818a

Muneto Izuhara, MD, MSc^a; Hisae Kihara Izuhara, MD^b; Keiko Tsuchie, MSc^a; Tomoko Araki, MSc^a; Tsukasa Ito, MD^a; Kouhei Sato, MD^a; Koji Otsuki, MD, PhD^a; Michiharu Nagahama, MD^a; Maiko Hayashida, MD, PhD^a; Sadayuki Hashioka, MD, PhD^a; Rei Wake, MD, PhD^a; Tomohiro Kimura, BSc^b; Shusaku Tsumoto, MD, PhD^c; Yoji Saito, MD, PhD^d; Masatoshi Inagaki, MD, PhD^a; Syoko Miura, MD^a

Educational Activity

Evidence-Based Treatment and Monitoring Strategies for Dementia-Related Psychosis

J Clin Psychiatry. 2021;82(3):AD19038BR4C.

Clive Ballard, MBChB, MMedSci, MRCPsych, MD

Educational Activity

Advances in Diagnosis of Alzheimer Disease and Emerging Treatment Targets

J Clin Psychiatry 2021;82(3):LI19012AS1C

Danielle Goldfarb, MD

Webcast

Talking With Patients and Care Partners About Treatment Goals and Challenges in Early-Stage Alzheimer Disease

J Clin Psychiatry. 2021;82(3):BG20044WC2C

Anna D. Burke, MD^a; Liana Apostolova, MD, MSc^b

Webcast

Early-Stage Alzheimer Primer: Pathophysiology, Diagnosis, and Assessment

J Clin Psychiatry. 2021;82(3):BG20044WC1C.

Liana Apostolova, MD, MSc

Webcast

Can Emerging Therapies Resolve Unmet Needs With Current Treatment in Early-Stage Alzheimer Disease?

J Clin Psychiatry 2021;82(3):BG20044WC3C

Anna D. Burke, MD

Volume 82 • 2021 • 3

Meta-Analysis

Marine Omega-3 Fatty Acid Supplementation for Borderline Personality Disorder: A Meta-Analysis

Meta-Analysis of the Treatment of Posttraumatic Stress Disorder in Adults With Comorbid Severe Mental Illness

Systematic Review

A Systematic Review of Complex Polypharmacy in Bipolar Disorder: Prevalence, Clinical Features, Adherence, and Preliminary Recommendations for Practitioners

Original Research

Trends in Medication Prescribing in Patients With PTSD From 2009 to 2018: A National Veterans Administration Study

Insomnia, Suicidal Ideation, and Suicide Attempts in the Clinical Antipsychotic Trials of Intervention Effectiveness

Obsessive-Compulsive Disorder and Dementia Risk: A Nationwide Longitudinal Study

Divorce or Separation Following Postpartum Psychiatric Episodes: A Population-Based Cohort Study

Cross-Sectional Associations Among Symptoms of Pain, Irritability, and Depression and How These Symptoms Relate to Social Functioning and Quality of Life: Findings From the EMBARC and STRIDE Studies and the VitalSign6 Project

Antipsychotic Use and Bloodstream Infections Among Adult Patients With Chronic Obstructive Pulmonary Disease: A Cohort Study

Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder

Transdiagnostic Psychiatric Symptoms, Burnout, and Functioning in Frontline Health Care Workers Responding to the COVID-19 Pandemic: A Symptomics Analysis

Frailty as a Predictor of Mortality in Late-Life Depression: A Prospective Clinical Cohort Study

Impact of the COVID-19 Pandemic on Child and Adolescent Psychiatric Emergencies

Persons With Debt Burden Are More Likely to Report Suicide Attempt Than Those Without: A National Study of US Adults

Therapeutic Response Is Associated With Antipsychotic-Induced Weight Gain in Drug-Naive First-Episode Patients With Schizophrenia: An 8-Week Prospective Study

Academic Highlights

Addressing Patients’ Unmet Needs to Improve Outcomes in Schizophrenia

Perspective

The Epigenetic Connection to Black Disparity

Clinical and Practical Psychopharmacology

β-Blockers and the Risk of New-Onset Depression: Meta-analysis Reassures, but the Jury Is Still Out

Fluoxetine for Stroke: A Mixed Bag of Outcomes

ASCP Corner

Therapeutic Potential of Psychedelics in Treatment of Psychiatric Disorders, Part 2: Review of the Evidence

Case Report

A Change in Blood Carbamazepine Levels Associated With Cannabis Use: Implications for Clinical Practice

Letter to the Editor

Posttraumatic Stress Disorder Symptom Severity Does Not Predict Depression Improvement, but May Impact Clinical Response and Remission

Veterans With Comorbid Depression and PTSD Can Be Effectively Treated With TMS

It Is Too Early to Put Delirium Prophylaxis to Bed: Stronger Evidence Is Needed for Suvorexant

Studies Support the Use of Suvorexant for the Prevention of Delirium

Educational Activity

Evidence-Based Treatment and Monitoring Strategies for Dementia-Related Psychosis

Advances in Diagnosis of Alzheimer Disease and Emerging Treatment Targets

Webcast

Talking With Patients and Care Partners About Treatment Goals and Challenges in Early-Stage Alzheimer Disease

Early-Stage Alzheimer Primer: Pathophysiology, Diagnosis, and Assessment

Can Emerging Therapies Resolve Unmet Needs With Current Treatment in Early-Stage Alzheimer Disease?

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