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Letter to the Editor

A Case of Olanzapine-Induced Gestational Diabetes Mellitus in the Absence of Weight Gain

Mytilee P. Vemuri, MD, and Natalie L. Rasgon, MD, PhD

Published: December 14, 2007

Article Abstract

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Sir: Second-generation antipsychotics have been implicated in the development of obesity, diabetes mellitus, and insulin resistance. Pregnancy increases the risk for insulin resistance, sometimes resulting in gestational diabetes mellitus. We describe a case of a woman with bipolar disorder who developed gestational diabetes in the absence of significant weight gain while treated with olanzapine during 2 pregnancies.’ ‹

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Volume: 68

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