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The Journal of
Clinical Psychiatry
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The Journal of Clinical Psychiatry

Letter to the Editor May 15, 2007

Decreased Lipoprotein Lipase as a Risk Factor for Atypical Neuroleptic-Induced Hypertriglyceridemia

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J Clin Psychiatry 2007;68(5):802-802

Article Abstract

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Neuroleptics often increase appetite. This increased appetite can lead to severe hypertriglyceridemia in patients with uncommon congenital lipoprotein lipase (LPL) deficiency. During neuroleptic therapy, attention should be paid to the potential for severe hypertriglyceridemia (> 1000 mg/dL) that increases the risk of atherosclerosis and can cause fatal acute pancreatitis.1,2‘ ‹

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