This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Original Research

Fluvoxamine Attenuates Panic Induced by 35% CO2 Challenge

Henk J. Pols, MD; Roos C. Hauzer, MD; Jaap A. Meijer, MD; Kees Verburg, MD; and Eric J. Griez, MD

Published: November 15, 1996

Article Abstract

Background: The authors investigated whether 6 weeks of treatment with fluvoxamine would decrease the anxiogenic response to the 35% CO2 challenge in 11 patients with DSM-IIIR panic disorder with agoraphobia.

Method: The patients underwent a 35% CO2 challenge at baseline and again after 6 weeks of fluvoxamine treatment.

Results: The anxiogenic effect of CO2 was significantly (p < .05) reduced during fluvoxamine treatment.

Conclusion: The results suggest a relationship between the anxiogenic effect of CO2 and the therapeutic effect of fluvoxamine.

Volume: 57

Quick Links:

Continue Reading…

Subscribe to read the entire article


Buy this Article as a PDF