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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Scrambler Therapy for Neuropathic Pain
Case Report

May 26, 2026

Scrambler therapy is an innovative treatment option for patients with chronic neuropathic pain, especially for those who do not respond to conventional interventions.
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PCC
Lorazepam vs. Diazepam in AUD
Original Research

May 26, 2026

Both lorazepam and diazepam led to more than 50% reduction in Clinical Institute Withdrawal Assessment for Alcohol–Revised scores within 5 days of initiation of treatment in alcohol dependence syndrome.
, , , et al
PCC
Alcohol Use Disorders in Primary Care
Rounds in the General Hospital

May 21, 2026

Patients with major depressive disorder and a comorbid AUD often present with more severe manifestations, including thoughts of suicide, co-occurring personality disorders, and higher rates of smoking.
, , , et al
PCC
ECT for Psychosis in Huntington Disease-Like 2
Case Report

May 19, 2026

A 47-year-old woman with genetically confirmed Huntington disease-like 2 had refractory psychosis and functional decline but responded well to electroconvulsive therapy.
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PCC
Manifestations Associated With CNS Lesions
Rounds in the General Hospital

May 19, 2026

Neuropsychiatric manifestations of brain metastases are varied, although certain symptoms can be associated with the brain region in which there is a metastasis; lesions that affect certain parts of…
, , , et al
PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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PCC
From Physical to Digital: Hoarding Phenomena in Obsessive-Compulsive Disorder
Case Report

May 14, 2026

This case illustrates how hoarding phenomenology can manifest in digital environments, which offer virtually unlimited storage, anonymity, and low visibility.
, , , et al
PCC
Differentiating Bipolar and Other Psychiatric Disorders
Rounds in the General Hospital ▶ Video

May 12, 2026

Diagnosis of bipolar spectrum disorder is often complicated, as most patients present for care during depressive episodes, which are more frequent than hypomanic or manic episodes.
, , , et al
PCC
Aripiprazole-Induced Pathological Gambling
Case Report

May 7, 2026

A 27-year-old man with a history of substance abuse developed a new-onset compulsive gambling pattern within weeks of starting aripiprazole.
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PCC
Strategies for Documenting the Medical Record
Rounds in the General Hospital

May 7, 2026

Documentation should be objective and relevant, especially in psychosocially complex cases—too much information can interfere with establishing the correct diagnosis and treatment plan, while too little increases risk of…
, , , et al
PCC
Readability of Self-Reported Psychosis Measures
Original Research

May 5, 2026

Most psychosis self-report measures are written above recommended reading levels, reducing accessibility for many patients with cognitive, educational, or symptomatic limitations.
, , , et al
PCC
Clozapine-Associated Pulmonary Embolism
Case Report

May 5, 2026

A 48-year-old woman with schizoaffective disorder taking clozapine developed acute pulmonary embolism despite negative D-dimer results.
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