The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Persistent Insomnia in an Elderly Man With HIV
Case Report

October 30, 2025

An 80-year-old man with receiving antiretroviral therapy for HIV since the mid-1990s reported complete inability to sleep, leading to psychological distress and suicidal ideation.
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PCC
Cerebrotendinous Xanthomatosis: Unraveling Prominent Neuropsychiatric Symptoms and MCI
Case Report

October 30, 2025

A 51-year-old woman with an 8-month history of significant cognitive decline and behavioral changes, including forgetfulness, irritability, and anger outbursts, received an initial diagnosis of MCI.
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PCC
Choosing a Pharmacologic Strategy for Psychosis
Rounds in the General Hospital

October 28, 2025

Find out which antipsychotic agent to prescribe to your patient with psychosis and learn how to balance the concepts of efficacy, tolerability, and cost.
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PCC
Impact of Hypotension on Cognitive Function
Rounds in the General Hospital

October 23, 2025

Hypotension acts synergistically to affect mental status by compounding problems with gas exchange, neurovascular dynamics, neuronal metabolism, and neurotoxicity.
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PCC
Neuropsychiatric Challenges of Friedreich’s Ataxia
Case Report

October 23, 2025

Management of behavioral symptoms in Friedreich’s ataxia patients requires a nuanced approach that integrates psychiatric care with traditional neurological treatment.
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PCC
Cognitive Distortions in Physician Guilt
Original Research

October 21, 2025

This study examines examples of physician guilt in television and movies and identifies examples of cognitive distortions to help readers gain insight into their own potential feelings of guilt.
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PCC
Fluoxetine-Induced Extrapyramidal Symptoms
Case Report

October 21, 2025

This case highlights the underrecognized risk of extrapyramidal symptoms, particularly drug-induced parkinsonianism, associated with fluoxetine.
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PCC
Managing Somatic Delusions
Rounds in the General Hospital

October 16, 2025

Management of somatic delusions involves a multimodal treatment approach incorporating pharmacotherapy, somatic treatments, and psychotherapy.
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PCC
NMS After Clozapine and ECT
Case Report

October 16, 2025

This case describes the diagnostic challenges of atypical neuroleptic malignant syndrome in a patient with schizophrenia and the potential interaction between clozapine and ECT.
PCC
Trigeminal Neuralgia in MS With OUD
Case Report

October 14, 2025

A 54-year-old woman with MS presented to the ED with a 6-week history of progressively worsening left facial pain. While responsive to opiates, she had a history of OUD.
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PCC
Incubus Syndrome in a Man With Alcohol Dependence
Case Report

October 14, 2025

The authors present a rare case of a 36-year-old man with alcohol dependence who developed multisensory hallucinations characteristic of incubus syndrome.
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PCC
N-Acetylcysteine for Psychogenic Polydipsia
Case Report

October 9, 2025

The authors describe the clinical management of an outpatient with diagnoses of psychogenic polydipsia, schizophrenia, mild intellectual and developmental disability, and autism spectrum disorder.
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Consensus Report on XT Use in Practice

Read the full report
Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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