The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for CNS Disorders

PCC
Impact of Religious Practices on Health
Rounds in the General Hospital

Impact of Religious Practices on Health

August 4, 2026

The importance of patients’ spiritual and religious practices is frequently under-appreciated by health care providers. Read this case vignette and discussion to find out more.
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PCC
Testosterone-Induced Psychosis in Klinefelter Syndrome
Case Report

Testosterone-Induced Psychosis in Klinefelter Syndrome

July 30, 2026

The authors report a rare case of acute psychosis following long-term parenteral testosterone replacement in a patient with undiagnosed Klinefelter syndrome.
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PCC
Abrupt Smoking Cessation With Tirzepatide
Case Report

Abrupt Smoking Cessation With Tirzepatide

July 30, 2026

The authors present a case of sudden, sustained smoking cessation associated with the initiation of tirzepatide in a 53-year-old woman.
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PCC
Decision-Making Capacity in the Operating Room
Case Report

Decision-Making Capacity in the Operating Room

July 28, 2026

This case illustrates that patients may retain decision-making even when refusing life-sustaining interventions in emergent contexts
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PCC
Amiodarone-Induced Thyrotoxicosis and Mania
Case Report

Amiodarone-Induced Thyrotoxicosis and Mania

July 28, 2026

A 66-year-old man diagnosed with amiodarone-induced thyrotoxicosis who presented to the emergency department with symptoms of mania.
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PCC
Reducing Screen Time in Children With Borderline IQ
Original Research

Reducing Screen Time in Children With Borderline IQ

July 23, 2026

In this RCT, the Parent Mediated Screen Time Usage Module demonstrated significant efficacy in reducing screen time and improving associated behavioral and health outcomes among children with borderline IQ.
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PCC
Clinical Perspectives on Internet Gaming Disorder
Original Research

Clinical Perspectives on Internet Gaming Disorder

July 23, 2026

Psychiatric providers demonstrate greater internet gaming disorder–related confidence and diagnostic familiarity than internal medicine providers, identifying a specialty-based gap in clinical preparedness.
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PCC
Psychometric Properties of the Brazilian BSL-23
Original Research

Psychometric Properties of the Brazilian BSL-23

July 21, 2026

Findings support the validity, reliability, and structural stability of the Brazilian version of the Borderline Symptom List 23, expanding access to the assessment of borderline symptoms in Brazil.
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PCC
Modafinil for Hypoactive Delirium in the ICU
Case Report

Modafinil for Hypoactive Delirium in the ICU

July 21, 2026

A 57-year-old woman with severe hypoactive delirium rapidly improved following a split-dosing strategy of modafinil.
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PCC
Mirtazapine-Induced Severe Hyponatremia
Case Report

Mirtazapine-Induced Severe Hyponatremia

July 16, 2026

A 30-year-old man developed severe hyponatremia after starting mirtazapine, highlighting the importance of closely monitoring sodium levels when starting any antidepressant in patients already taking oxcarbazepine.
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PCC
Cocaine-Associated Rectal Foreign Body Insertion
Case Report

Cocaine-Associated Rectal Foreign Body Insertion

July 16, 2026

This case highlights how recurrent surgical presentations related to substance-associated compulsive behavior can outpace sustained, longitudinal behavioral intervention, particularly when psychiatric and addiction care are not integrated early.
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PCC
Freeze Attacks in Stiff Person Spectrum Disorder
Case Report

Freeze Attacks in Stiff Person Spectrum Disorder

July 14, 2026

A 43-year-old woman with stiff person spectrum disorder developed agoraphobia after “freeze attacks” in public, highlighting the need to screen these patients for anxiety and the role of CBT…
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