The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Fluoxetine-Induced Extrapyramidal Symptoms
Case Report

October 21, 2025

This case highlights the underrecognized risk of extrapyramidal symptoms, particularly drug-induced parkinsonianism, associated with fluoxetine.
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PCC
Managing Somatic Delusions
Rounds in the General Hospital

October 16, 2025

Management of somatic delusions involves a multimodal treatment approach incorporating pharmacotherapy, somatic treatments, and psychotherapy.
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PCC
NMS After Clozapine and ECT
Case Report

October 16, 2025

This case describes the diagnostic challenges of atypical neuroleptic malignant syndrome in a patient with schizophrenia and the potential interaction between clozapine and ECT.
PCC
Trigeminal Neuralgia in MS With OUD
Case Report

October 14, 2025

A 54-year-old woman with MS presented to the ED with a 6-week history of progressively worsening left facial pain. While responsive to opiates, she had a history of OUD.
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PCC
Incubus Syndrome in a Man With Alcohol Dependence
Case Report

October 14, 2025

The authors present a rare case of a 36-year-old man with alcohol dependence who developed multisensory hallucinations characteristic of incubus syndrome.
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PCC
N-Acetylcysteine for Psychogenic Polydipsia
Case Report

October 9, 2025

The authors describe the clinical management of an outpatient with diagnoses of psychogenic polydipsia, schizophrenia, mild intellectual and developmental disability, and autism spectrum disorder.
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PCC
Mosaic Turner Syndrome and Schizophrenia
Case Report

October 7, 2025

This case adds to the literature on Turner syndrome and psychosis and is an example of the heterogeneity of individuals who meet the criteria for treatment-resistant schizophrenia.
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PCC
When a Headache Isn’t Just a Headache
Case Report

October 7, 2025

A 70-year-old woman experienced progressive headache and systemic symptoms after several days of high-dose ibuprofen administration.
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PCC
Access to Primary Care in First-Episode Psychosis
Original Research

October 2, 2025

Improving engagement in primary care is critical for young adults with first-episode psychosis to establish beneficial patterns of health care use and timely access to preventative care.
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PCC
Talking to Your Patients About HSCT
Rounds in the General Hospital

September 30, 2025

If you have been unsure about what you should discuss with your patients who might undergo hematopoietic stem cell transplantation, then this case and discussion should prove useful.
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PCC
Valproate-Induced Hypermelanosis
Case Report

September 30, 2025

The authors present 2 cases of hyperpigmentation induced by sodium valproate and valproic acid.
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PCC
Dexamethasone and Cyproheptadine Misuse
Case Report

September 25, 2025

This case provides rare insight into the complications and delayed recognition associated with long-term, nonpsychoactive substance misuse, despite overt harm and a family history of addiction treatment.
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Consensus Report on XT Use in Practice

Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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