The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Benzodiazepine-Induced Neurologic Dysfunction
Case Report

November 27, 2025

This case illustrates how benzodiazepine-induced neurologic dysfunction and benzodiazepine use disorder can coexist, emphasizing the importance of distinguishing between them to guide diagnosis and management.
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PCC
From Varenicline to Neuroleptic Malignant Syndrome
Case Report

November 27, 2025

This case highlights the complexity of diagnosing atypical neuroleptic malignant syndrome in high-risk individuals after sudden cessation of varenicline and cigarette smoking.
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PCC
Comorbidities Obscure Autism Diagnosis
Case Report

November 25, 2025

A 14-year-old boy with longstanding psychotic illness, posttraumatic stress from adverse social experiences, and suicidality presented for neuropsychiatric assessment.
PCC
Impact of Patient Suicide on Mental Health Professionals
Original Research

November 20, 2025

Patient suicide can cause lasting emotional and professional distress in mental health professionals due to their unique relationship with the patient.
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PCC
Psychosis or Multiple System Atrophy?
Case Report

November 20, 2025

A 67-year-old woman presented with altered mental status, hallucinations, and hyperalgesia of the bilateral lower legs and was subsequently diagnosed with multiple system atrophy.
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PCC
Religious Preoccupation in Adolescence
Case Report

November 18, 2025

A 16-year-old boy developed new-onset psychosis of religious preoccupation and delusions.
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PCC
Clozapine Withdrawal–Induced Catatonia
Case Report

November 18, 2025

A patient with treatment-resistant schizophrenia developed persistent catatonia after sudden cessation of clozapine, highlighting the challenges in management and the potential role of clozapine reintroduction.
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PCC
Lumateperone-Induced Urticarial Rash in Schizophrenia
Case Report

November 13, 2025

This report describes an instance of acute generalized urticaria immediately following an initial dose of lumateperone in a 43-year-old man with schizophrenia.
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PCC
Talking to Pregnant Patients About Substance Use
Rounds in the General Hospital

November 11, 2025

A 33-year-old pregnant woman presented to the obstetric triage unit at 28 weeks. She and her partner reported that this pregnancy was going smoothly except for one thing: she…
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PCC
Talking to Patients About Inflammatory Bowel Diseases
Rounds in the General Hospital

November 6, 2025

Find out what triggers irritable bowel diseases and how your patients can manage their GI symptoms and utilize psychotropic agents in this comprehensive guide.
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PCC
Psychological Sequelae of Drone Attacks
Rounds in the General Hospital

November 6, 2025

Read about a newly emerging form of combat stress, one shaped by the relentless and psychologically corrosive nature of modern drone warfare.
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PCC
Schizophrenia With Diphenhydramine Abuse
Case Report

November 4, 2025

This report examines the effects of clozapine on diphenhydramine dependence in a 33-year-old patient with schizophrenia.

Consensus Report on XT Use in Practice

Read the full report
Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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