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Letter to the Editor

Aripiprazole as the Causative Agent of Neuroleptic Malignant Syndrome

Daniel Molina, MD, LT; Leslie E. Tingle, MD; and Xiaohui Lu, MD

Published: April 16, 2007

Article Abstract

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Sir: Neuroleptic malignant syndrome (NMS) is a rare and potentially life-threatening neurologic emergency commonly associated with the use of antipsychotic medications. As a class, atypical antipsychotic agents have lower associated rates of extrapyramidal symptoms and are less likely to induce NMS as compared to conventional antipsychotics. One of the newest agents in the atypical antipsychotic class is aripiprazole

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