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Letter to the Editor

Hypothyroidism in Patients With Asthma and Major Depressive Disorder

Rebecca J. Oppedal, BS; David A. Khan, MD; and E. Sherwood Brown, MD, PhD

Published: December 14, 2007

Article Abstract

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Sir: Approximately 8% of depressed patients have at leastsubclinical hypothyroidism,1 compared to only 5% of the generalpopulation.2 An epidemiologic study found that hypothyroidismmay also be associated with asthma,3 although thisassociation is less well established than the association with depression.Depression is extremely common in asthma patients.4

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