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Letter to the Editor

Oxcarbazepine-Induced Reversible Anorgasmia and Ejaculatory Failure: A Case Report

Kamaljeet Boora, MD; Kimberley Chiappone, MD; and Steven L. Dubovsky, MD

Published: August 19, 2009

Article Abstract

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To the Editor: Psychotropic drugs are well known to affect sexual functioning1 and may contribute to patient noncompliance. The serotonin reuptake inhibitor antidepressants are particularly known for their effects on orgasm.2 Much less is known about adverse sexual effects of anticonvulsants, although a few case reports suggest that topiramate,3 gabapentin, 4 and carbamazepine5 may cause ejaculatory failure, though these cases are mainly from patient populations with epilepsy.

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