Partial Seizures With Secondary Generalization While on Treatment With Clozapine and Sertraline: A Case Report

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Sir: Clozapine is known to cause generalized and myoclonic seizures. Here we report a neurologically normal individual who developed partial seizures with secondary generalization while receiving clozapine and sertraline.

Case report. Mr. A, a 19-year-old man with paranoid schizophrenia whose psychotic symptoms had remitted with clozapine (300 mg/day), presented in 2007 with severe obsessive impulses to jump from heights.

Prim Care Companion J Clin Psychiatry 2009;11(3):127-128