Original Research
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Recently published articles about Original Research
Original Research
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
May 4, 2026
In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
Original Research
Phase 2b Study to Evaluate Basmisanil as Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia
April 15, 2026
Although basmisanil did not improve cognitive deficits, the results offer insight into factors that should facilitate design of more informative trials.
Original Research
Nonsuicidal Self-Injury and Its Association with Suicidal Ideation and Negative Affect
April 8, 2026
Desire to self-harm was associated with nonsuicidal self-injury (NSSI) episodes. Further, NSSI was related to higher negative affect and negative interpersonal experience, which decreased across follow-up.
Original Research
Using Natural Language Processing to Evaluate Differences in Psychotherapeutic Services for PTSD in a Suicide-Risk-Stratified Veteran Sample
April 8, 2026
Psychotherapeutic care for PTSD differed for patients who did and did not die by suicide, suggesting the importance of developing risk-tier-specific care.
Original Research
Correlates and Predictors of Criminal Legal Involvement in First-Episode Psychosis
March 30, 2026
More than 10% of people with first-episode psychosis are involved in the legal system before (11%) and while (14%) receiving mental health treatment, which can interrupt access to specialty...
