Letter to the Editor November 17, 2016

A Prospective Study of Antidepressant Adherence and Suicidal Ideation Among Adults

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Prim Care Companion CNS Disord 2016;18(6):doi:10.4088/PCC.16l01935

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To the Editor: Previous studies examining the link between antidepressant medication and suicidal ideation among youth have been inconclusive. Earlier studies demonstrated an association leading to the US Food and Drug Administration’s black box warning, but more recent studies have suggested an inverse association, such that antidepressants may reduce suicide risk. Additionally, most studies among adults suggest that antidepressants decrease suicidal ideation during the immediate period following initiation.