Aripiprazole-Induced Hypersexuality

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To the Editor: Aripiprazole differs from other antipsychotics because of its unique pharmacologic profile; it acts as a partial agonist of the dopamine D2 receptors. The literature shows a surge of reports describing impulse-control behaviors with dopamine receptor agonist drugs, and the US Food and Drug Administration (FDA) recently issued a warning regarding these behaviors. In this report, we describe the case of a patient with bipolar disorder who developed hypersexuality following aripiprazole treatment.