Letter to the Editor Difficult to Treat Depression April 30, 2015

A Case of Electroconvulsive Therapy-Resistant Depression Responding to Multiple Dopaminergic Medications

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Prim Care Companion Disord 2015;17(2):doi:10.4088/PCC.14l01745

Article Abstract

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To the Editor: Treatment-resistant depression is common, challenging, and difficult to treat. In this case report, we discuss the role of using multiple dopaminergic medications to achieve remission of depression. To our knowledge, this is the first case report on the use of combination therapy (clomipramine, dextroamphetamine, pramipexole, and aripiprazole) for electroconvulsive therapy-resistant unipolar depression.