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Letter to the Editor

Partial Seizures With Secondary Generalization While on Treatment With Clozapine and Sertraline: A Case Report

Vivek H. Phutane, MBBS; Channaveerachari Naveen Kumar, MD, DPM; Jagadisha Thirthalli, MD; Seemendra Kumar Mahato, MD; and Sanjib Sinha, MD, DM

Published: June 17, 2009

Article Abstract

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Sir: Clozapine is known to cause generalized and myoclonic seizures. Here we report a neurologically normal individual who developed partial seizures with secondary generalization while receiving clozapine and sertraline.

Case report. Mr. A, a 19-year-old man with paranoid schizophreniawhose psychotic symptoms had remitted with clozapine(300 mg/day), presented in 2007 with severe obsessive impulses to jump from heights.

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