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Letter to the Editor

Quetiapine-Induced Bradycardia Without QT Interval Prolongation in an Elderly Woman

André Janse, MD, and Radboud M. Marijnissen, MD

Published: August 19, 2009

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To the Editor: Bradycardia has recently been reportedas a rare but severe adverse effect of atypical antipsychoticslike risperidone,1,2 olanzapine,3 and clozapine.4 Most casereports describe bradycardia with QT interval prolongation.1-5 Until now, the mechanism of this bradyarrhythmogeniccharacter of atypical antipsychotics has not fullybeen understood.

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