Access icon

Case Report May 24, 2022

Spontaneous Ejaculation Associated With Atomoxetine

; ;

Prim Care Companion CNS Disord 2022;24(3):21cr03136

  1. Strattera (atomoxetine) [package insert]. Lilly LLC; 2020.
  2. Clemow DB, Bushe C, Mancini M, et al. A review of the efficacy of atomoxetine in the treatment of attention-deficit/hyperactivity disorder in children and adult patients with common comorbidities. Neuropsychiatr Dis Treat. 2017;13:357–371. PubMed CrossRef
  3. Oosterhuis I, Heijting L, Van Puijenbroek EP. Spontaneous ejaculation with the use of ADHD drugs. Drug Saf. 2009;32(10):409.
  4. Clement P, Giuliano F. Physiology and pharmacology of ejaculation. Basic Clin Pharmacol Toxicol. 2016;119(suppl 3):18–25. PubMed CrossRef
  5. Sivrioglu EY, Topaloglu VC, Sarandol A, et al. Reboxetine induced erectile dysfunction and spontaneous ejaculation during defecation and micturition. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(2):548–550. PubMed CrossRef
  6. Yaylacı F, Şahbudak B, Küçük Ö. Spontaneous ejaculation induced with atomoxetine. Psychopharmacol Bull. 2020;50(1):40–43. PubMed
  7. McGrane IR, Campbell TJ. Probable genitourinary adverse events associated with atomoxetine in an adult male: a case report. J Pharm Pract. 2021;34(6):962–965. PubMed CrossRef
  8. MacDonald T, Wimalaguna PS, Akosile W. Case report: severe and treatment-resistant spontaneous ejaculation secondary to atomoxetine. Australas Psychiatry. 2019;27(2):198–199. PubMed CrossRef
  9. Oosterhuis I, Heijting L, van Puijenbroek E. Spontaneous ejaculation with the use of noradrenergic reuptake inhibitors. Eur J Clin Pharmacol. 2012;68(10):1461–1462. PubMed CrossRef
  10. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30(2):239–245. PubMed CrossRef