A Case Report of Double Incontinence Associated With Clozapine

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Sir: Clozapine is known to be an effective agent in the treatment of refractory psychotic disorders. Although clozapine causes minimal extrapyramidal symptoms, adverse effects such as agranulocytosis, weight gain, hypersalivation, seizures, and urinary incontinence form obstacles to patients’ compliance. Clozapine-induced urinary incontinence is a frequently reported side effect1; however, the literature is sparse about the combination of urinary and fecal incontinence.​

Prim Care Companion J Clin Psychiatry 2007;9(2):148