Original Research
Original Research
Outcomes and Practice Patterns of LAI Versus Oral Antipsychotics Among Patients With Bipolar I Disorder in the US
March 2, 2026
Long-acting injectable antipsychotics, especially second-generation formulations, are associated with reduced rehospitalization in bipolar I disorder compared to oral antipsychotics.
Original Research
Validation of the APREMDI Scale for Brazilian Portuguese
February 19, 2026
The APREMDI scale allows clinicians to quantitatively assess patients’ perceptions of respect and dignity during hospitalization, helping to identify subtle dignity violations that may compromise recovery and satisfaction.
Original Research
Factors Associated with Revisiting the Emergency Department due to Suicidal Behavior in Children and Adolescents
January 28, 2026
Within 6 months of the initial emergency department (ED) visit, 21.7% of patients who initially attended the ED for self-injurious thoughts and behaviors returned for the same reason.
Original Research
Geographic Differences in Cannabis Use and Cannabis Use Disorder in the US Veteran Population
January 19, 2026
Significant regional differences were observed in cannabis use and cannabis use disorder (CUD). Veterans in the Pacific region had the highest rates of cannabis use and CUD.
Original Research
Innovation in Psychiatric Drug Development: A Quantitative Analysis of FDA-Approved Psychiatric Drugs, 2012–2024
January 12, 2026
Innovation in psychiatric drug development in the past 13 years was limited, with most new drugs representing incremental advances rather than groundbreaking innovations.
Original Research
Lack of Generalizability of PTSD Treatment Trials: The Recent Brexpiprazole-Sertraline Trials as an Example
November 26, 2025
In an outpatient psychiatry sample, nearly 95% of patients who want treatment for PTSD would not have qualified for the trials of brexpiprazole-sertraline for PTSD.
