Original Research
Original Research
Differentiating Subtypes of MDD Using Serum Biomarkers
June 23, 2025
Significant differences in biomarker profiles were observed across MDD subtypes: the melancholic subtype showed higher cortisol levels and lower serotonin levels, and the atypical subtype showed elevated levels of...
Original Research
Bright Light Therapy in the Morning or Midday for Nonseasonal Depression in Bipolar Disorder
June 23, 2025
Bright light therapy is well tolerated in bipolar disorder, starting at 45 minutes/day, with only 6% of patients experiencing a hypomanic switch and 13% experiencing subsyndromic symptoms, which resolved...
Original Research
Association Between Adult Sexual Assault and Psychiatric Disorders: Results From NESARC
June 16, 2025
Among participants who experienced adult sexual assault, 85.25% had at least 1 lifetime psychiatric disorder. In women, the strongest associations were with PTSD, borderline personality disorder, and suicide attempts,...
Original Research
Cognitive Behavioral Therapy for Insomnia with Prolonged Exposure Compared to Sleep Hygiene and Prolonged Exposure
June 4, 2025
On average, participants had reductions in PTSD symptoms, with no differences between the treatment groups. CBT for insomnia with prolonged exposure produced greater reductions in insomnia symptoms and increases...
Original Research
Outpatient Ketamine Prescribing Practices in Psychiatry in the US: A Nationwide Survey Study
May 26, 2025
There is significant variability in ketamine treatment in the community including indications, treatment duration, formulation, and setting of use. Increased oversight and specific practice guidelines are needed to ensure...
Original Research
Preference for Lisdexamfetamine vs CBT for Binge-Eating Disorder
May 7, 2025
CBT and pharmacotherapy with lisdexamfetamine resulted in significant improvements in binge-eating disorder. Participants’ preferences for treatments were not associated with sociodemographic or clinical characteristics and did not moderate treatment...
Original Research
Defense Mechanisms and Common Psychiatric Disorders
April 28, 2025
Individuals with mood, anxiety, or substance use disorders generally had a higher prevalence of defense mechanisms than those with no disorders. Defense mechanisms and psychiatric disorders represent correlated but...
