The Journal of
Clinical Psychiatry

Volume 86 • 2025 • 4

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial

J Clin Psychiatry 2025;86(4):25m15848

Suresh Durgam, MD; Willie R. Earley, MD; Susan G. Kozauer, MD; Changzheng Chen, PhD; Hassan Lakkis, PhD; Roger S. McIntyre, MD; Stephen Stahl, MD, PhD

<em>N</em>-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

Original Research

N-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

J Clin Psychiatry 2025;86(4):25m15803

Sudie E. Back, PhD; Kevin Gray, MD; Amber M. Jarnecke, PhD; Tanya C. Saraiya, PhD; Elizabeth J. Santa Ana, PhD; Therese Killeen, PhD; Jane E. Joseph, PhD; James J. Prisciandaro, PhD; Delisa G. Brown, PhD; Paul J. Nietert, PhD; Tracy Stecker, PhD; Alex Rothbaum, PhD; Jennifer L. Jones, MD; Julianne C. Flanagan, PhD; Kathleen T. Brady, MD, PhD

ASCP Corner

What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?

ASCP Corner

What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?

J Clin Psychiatry 2025;86(4):25ac15936

Joseph F. Goldberg, MD; Holly A. Swartz, MD; Rajnish Mago, MD; Roger S. McIntyre, MD; Gin S. Malhi, MD; Joshua D. Rosenblat, MD; Marlene P. Freeman, MD; Eduard Vieta, MD; Michael E. Thase, MD; Mauricio Tohen, MD; Leslie Citrome, MD, MPH