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Screening for Early Alzheimer’s Disease: Is There Still a Role for the Mini-Mental State Examination?

Aaron D. Benson, BS; Melissa J. Slavin, PhD; Thanh-Thu Tran, BS; Jeffrey R. Petrella, MD; and P. Murali Doraiswamy, MD

Published: April 1, 2005

Article Abstract

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In light of the continuing rise in the population of elderlyindividuals in the United States and the of impaired cognitive function to diminishone’s qualityof life, accurate and effective screening for early recognitionand differentiation between normal age-relatedcognitive decline, mild cognitive impairment (MCI), mildAlzheimer’s disease, and other causes of cognitive declineis desirable. The Mini-Mental State Examination(MMSE)1 is one of the most widely used tools implementedby physicians to evaluate a patient’s cognitive status.24threat

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