Letter to the Editor May 17, 2018

Diaphoresis: A Presentation of Serotonin Syndrome From Vortioxetine

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Prim Care Companion CNS Disord 2018;20(3):17l02191

Article Abstract

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To the Editor: The clinical presentation of serotonin syndrome spans a wide spectrum—from benign to lethal—due to increased serotonergic activity in the central nervous system. The classical features of serotonin syndrome are indistinguishable in the early stages, posing a diagnostic challenge. We present the case of a patient who developed serotonin syndrome while taking vortioxetine 10 mg/d (therapeutic dose).