Case Report

PCC
A Case of AVM, Hemichorea, and Depression
Case Report

December 4, 2025

A 30-year-old man presented with rapid, involuntary jerky movements on his right side, exacerbated by stress and absent during sleep, as well as low mood, hopelessness, poor concentration, anhedonia,...
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PCC
Complexities of Serotonin Syndrome
Case Report

December 4, 2025

A 58-year-old man presented to the ED due to muscle stiffness, uncontrollable limb movements, and the sensation as if his body was on fire.
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PCC
Benzodiazepine-Induced Neurologic Dysfunction
Case Report

November 27, 2025

This case illustrates how benzodiazepine-induced neurologic dysfunction and benzodiazepine use disorder can coexist, emphasizing the importance of distinguishing between them to guide diagnosis and management.
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PCC
From Varenicline to Neuroleptic Malignant Syndrome
Case Report

November 27, 2025

This case highlights the complexity of diagnosing atypical neuroleptic malignant syndrome in high-risk individuals after sudden cessation of varenicline and cigarette smoking.
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PCC
Comorbidities Obscure Autism Diagnosis
Case Report

November 25, 2025

A 14-year-old boy with longstanding psychotic illness, posttraumatic stress from adverse social experiences, and suicidality presented for neuropsychiatric assessment.
PCC
Psychosis or Multiple System Atrophy?
Case Report

November 20, 2025

A 67-year-old woman presented with altered mental status, hallucinations, and hyperalgesia of the bilateral lower legs and was subsequently diagnosed with multiple system atrophy.
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PCC
Religious Preoccupation in Adolescence
Case Report

November 18, 2025

A 16-year-old boy developed new-onset psychosis of religious preoccupation and delusions.
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PCC
Clozapine Withdrawal–Induced Catatonia
Case Report

November 18, 2025

A patient with treatment-resistant schizophrenia developed persistent catatonia after sudden cessation of clozapine, highlighting the challenges in management and the potential role of clozapine reintroduction.
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PCC
Lumateperone-Induced Urticarial Rash in Schizophrenia
Case Report

November 13, 2025

This report describes an instance of acute generalized urticaria immediately following an initial dose of lumateperone in a 43-year-old man with schizophrenia.
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PCC
Schizophrenia With Diphenhydramine Abuse
Case Report

November 4, 2025

This report examines the effects of clozapine on diphenhydramine dependence in a 33-year-old patient with schizophrenia.
PCC
Persistent Insomnia in an Elderly Man With HIV
Case Report

October 30, 2025

An 80-year-old man with receiving antiretroviral therapy for HIV since the mid-1990s reported complete inability to sleep, leading to psychological distress and suicidal ideation.
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PCC
Cerebrotendinous Xanthomatosis: Unraveling Prominent Neuropsychiatric Symptoms and MCI
Case Report

October 30, 2025

A 51-year-old woman with an 8-month history of significant cognitive decline and behavioral changes, including forgetfulness, irritability, and anger outbursts, received an initial diagnosis of MCI.
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PCC
Neuropsychiatric Challenges of Friedreich’s Ataxia
Case Report

October 23, 2025

Management of behavioral symptoms in Friedreich’s ataxia patients requires a nuanced approach that integrates psychiatric care with traditional neurological treatment.
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PCC
Fluoxetine-Induced Extrapyramidal Symptoms
Case Report

October 21, 2025

This case highlights the underrecognized risk of extrapyramidal symptoms, particularly drug-induced parkinsonianism, associated with fluoxetine.
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PCC
NMS After Clozapine and ECT
Case Report

October 16, 2025

This case describes the diagnostic challenges of atypical neuroleptic malignant syndrome in a patient with schizophrenia and the potential interaction between clozapine and ECT.
PCC
Trigeminal Neuralgia in MS With OUD
Case Report

October 14, 2025

A 54-year-old woman with MS presented to the ED with a 6-week history of progressively worsening left facial pain. While responsive to opiates, she had a history of OUD.
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PCC
Incubus Syndrome in a Man With Alcohol Dependence
Case Report

October 14, 2025

The authors present a rare case of a 36-year-old man with alcohol dependence who developed multisensory hallucinations characteristic of incubus syndrome.
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PCC
N-Acetylcysteine for Psychogenic Polydipsia
Case Report

October 9, 2025

The authors describe the clinical management of an outpatient with diagnoses of psychogenic polydipsia, schizophrenia, mild intellectual and developmental disability, and autism spectrum disorder.
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PCC
Mosaic Turner Syndrome and Schizophrenia
Case Report

October 7, 2025

This case adds to the literature on Turner syndrome and psychosis and is an example of the heterogeneity of individuals who meet the criteria for treatment-resistant schizophrenia.
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PCC
When a Headache Isn’t Just a Headache
Case Report

October 7, 2025

A 70-year-old woman experienced progressive headache and systemic symptoms after several days of high-dose ibuprofen administration.
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PCC
Valproate-Induced Hypermelanosis
Case Report

September 30, 2025

The authors present 2 cases of hyperpigmentation induced by sodium valproate and valproic acid.
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PCC
Dexamethasone and Cyproheptadine Misuse
Case Report

September 25, 2025

This case provides rare insight into the complications and delayed recognition associated with long-term, nonpsychoactive substance misuse, despite overt harm and a family history of addiction treatment.
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PCC
Neuropsychiatric Symptoms of Morquio Syndrome
Case Report

September 25, 2025

A 70-year-old man with Morquio syndrome presented with mood instability and behavioral changes and became a significant nursing challenge.
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PCC
ECT for Auditory Hallucinations
Case Report

September 23, 2025

A 19-year-old patient with Turner syndrome, schizophrenia and MDD presented for an ECT evaluation after multiple pharmacologic treatments failed to control her refractory auditory hallucinations, which had persisted for...
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Consensus Report on XT Use in Practice

Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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