Case Report

Caffeine for ICI Encephalitis

March 5, 2026

With the increased use of immune checkpoint inhibitors, the potential for aseptic encephalitis poses a unique challenge to patient rehabilitation.

Brandon J. Goodwin, Dan Yacubovich, Fatimah B. Alhassan, et al

Case Report

Misophonia With Psychiatric Comorbidities

March 3, 2026

This case highlights the need for enhanced recognition of misophonia, integrated care pathways, and improved mental health infrastructure in low- and middle-income countries.

Palwasha Asghar

Case Report

Intranasal Tapentadol Dependence

February 26, 2026

The authors present 2 cases of intranasal tapentadol dependence marked by rapid tolerance and significant physical and psychological issues.

Shivam Gakkhar, Aishwariya Jha, Vasuki Pazhanivel, et al

$Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD$

Case Report

Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD

February 23, 2026

Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.

Ngo Cheung

Case Report

Calcineurin Inhibitor–Induced Psychosis

February 17, 2026

The authors report a case of delayed and recurrent calcineurin inhibitor–induced psychosis with both tacrolimus and cyclosporine, highlighting the need to better understand host vulnerability and risk stratification.

Nicole M. Khanna, Aniruddha Deka

Case Report

Arm EMG and Detection of REM Sleep Without Atonia

February 17, 2026

This case highlights the importance of utilizing arm EMG to accurately detect REM sleep without atonia, as REM sleep behavior disorder often precedes the development of α-synucleinopathies, such as...

John A. Das, Arminder Johal, Stephanie M. Stahl

Case Report

Long-Term High-Intensity Drinking

February 12, 2026

This case underscores the need to recognize episodic high-intensity alcohol use as a clinically relevant presentation that carries medical and social risks despite the absence of daily drinking.

José Abrantes, Joana Teixeira

Case Report

Periodic Catatonia in an Adult With Autism

February 3, 2026

The authors report a case of periodic catatonia in a 30-year-old man with autism spectrum disorder, with no other identifiable psychiatric or neurological comorbidities, that responded to lithium prophylaxis.

Anirudh Bakam, Sachi Raina, YC Janardhan Reddy

Case Report

When the Labs Don’t Add Up: Factitious Disorder and Successful Treatment

January 27, 2026

This case of a 37-year-old woman, who presented to the ED with recurrent syncope and acute kidney injury, demonstrates successful long-term treatment of factitious disorder, highlighting the complexities of...

Garrett Hill, Spencer Milanak, Kaushal Shah, et al

Case Report

High-dose Veterinary AMP Dependence

January 27, 2026

A 41-year-old man self-administered mega-doses of veterinary adenosine monophosphate over an extended period and experienced intense withdrawal and psychological symptoms after discontinuation.

Shobit Garg, Apoorva Jawandha, Preeti Mishra, et al

Case Report

Basal Ganglia Stroke With Lower Motor Neuron Features

January 22, 2026

A 60-year-old man exhibited left-sided toe walking and right-sided weakness despite previous history of left sided basal ganglia stroke, challenging the notion that adult toe walking is a hallmark...

Diana B. Riestra, Jessica Mitchell, Juan M. Riestra, et al

Case Report

Benign Ethnic Neutropenia and Clozapine

January 22, 2026

This case highlights the importance of recognizing benign ethnic neutropenia to prevent unnecessary clozapine discontinuation.

Marta Loureiro Ribeiro, Sofia Albuquerque, Rodrigo Saraiva, et al

Case Report

Depression Remission in Parkinson Disease With iTBS

January 20, 2026

Two cases demonstrate the potential for intermittent theta burst transcranial magnetic stimulation to rapidly reverse treatment-resistant depression in patients with Parkinson disease.

Joshua B. Robbins, Imran S. Khawaja

Case Report

Lithium-Induced Rash: Unveiling the Dermatological Dilemma

January 20, 2026

A 32-year-old woman recently diagnosed with bipolar affective disorder developed lithium-induced rash that did not recur on rechallenge.

Anirban Saha, Lakshmi Nirisha, Shrayasi Das, et al

Case Report

Skin Picking in Profound Intellectual Disability

January 15, 2026

A 39-year-old woman with profound intellectual disability and delayed developmental milestones presented with late-onset severe dermatillomania.

M. Vaseel, N. A. Uvais

Case Report

LSD-Induced Catatonia in an Adolescent

January 13, 2026

A 16-year-old boy experienced catatonia associated with lysergic acid diethylamide use.

Megan Hophing, Ali Imam Awan, Meghana Damaraju, et al

Case Report

Cotard Syndrome in Schizophrenia

January 8, 2026

A 42-year-old woman with schizophrenia and multiple prior hospitalizations presented with worsening psychosis and physical aggression toward her mother.

Mark Rosenfeld, Hobab Aslam, Raheel Imtiaz Memon

Case Report

Transient Loss of Consciousness in an Adolescent with Pathological Intoxication

January 1, 2026

This case of atypical symptoms in a 15-year-old boy underscores the need to differentiate pathological intoxication from seizures and psychiatric conditions, emphasizing alcohol abstinence.

Rishab Yadav, Shruti Kumar, Shobit Garg

Case Report

Machine Madness: A Case of Artificial Intelligence Psychosis

December 30, 2025

A 41-year-old man with a history of substance-induced psychosis, developed symptoms of psychosis related to frequent occupational use of AI.

Matthew R. Caldwell, Patrick A. Ho

Case Report

A Case of Kratom Withdrawal

December 25, 2025

A 29-year-old man experienced kratom withdrawal that necessitated intensive care management and resulted in subsequent cardiac arrest.

Brandon J. Goodwin, Moiuz Chaudhri, Ankur Jain, et al

Case Report

Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration

December 18, 2025

The author presents a case of clozapine-induced QTc prolongation and discusses its relationship with serum clozapine concentration

Hirofumi Hirakawa

Case Report

Balancing Pragmatism and Ethics in Psychiatry

December 16, 2025

A psychiatrist strategically used a patient's internalized fear of extremism to redirect behavior during a manic episode.

N. A. Uvais

Case Report

Bupropion for Postpartum Depression and Narcolepsy

December 11, 2025

Bupropion was an effective pharmacologic therapy for narcolepsy with cataplexy in a 21-year-old woman with postpartum depression.

Jisselly Sanchez Salcedo, Kayleigh A. Watson, Bradley T. Miller, et al

Case Report

Unstable Lithium Levels in a Bodybuilder With Bipolar Disorder

December 11, 2025

This case highlights the importance of assessing dietary habits, supplement use, and potential anabolic steroid use, particularly in physically active patients undergoing lithium therapy.

Nicholas S. McDuffee, Aren A. Forster, Kaushal Shah

Case Report

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Case Report

Caffeine for ICI Encephalitis

Misophonia With Psychiatric Comorbidities

Intranasal Tapentadol Dependence

Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD

Calcineurin Inhibitor–Induced Psychosis

Arm EMG and Detection of REM Sleep Without Atonia

Long-Term High-Intensity Drinking

Periodic Catatonia in an Adult With Autism

When the Labs Don’t Add Up: Factitious Disorder and Successful Treatment

High-dose Veterinary AMP Dependence

Basal Ganglia Stroke With Lower Motor Neuron Features

Benign Ethnic Neutropenia and Clozapine

Depression Remission in Parkinson Disease With iTBS

Lithium-Induced Rash: Unveiling the Dermatological Dilemma

Skin Picking in Profound Intellectual Disability

LSD-Induced Catatonia in an Adolescent

Cotard Syndrome in Schizophrenia

Transient Loss of Consciousness in an Adolescent with Pathological Intoxication

Machine Madness: A Case of Artificial Intelligence Psychosis

A Case of Kratom Withdrawal

Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration

Balancing Pragmatism and Ethics in Psychiatry

Bupropion for Postpartum Depression and Narcolepsy

Unstable Lithium Levels in a Bodybuilder With Bipolar Disorder

Consensus Report on XT Use in Practice

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