The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
LSD-Induced Catatonia in an Adolescent
Case Report

January 13, 2026

A 16-year-old boy experienced catatonia associated with lysergic acid diethylamide use.
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PCC
Treatment and Referral for AUD in Primary Care
Rounds in the General Hospital

January 13, 2026

Explore which treatments are best for your patients with alcohol use disorders and when you should refer for specialized psychological or pharmacologic interventions.
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PCC
Cotard Syndrome in Schizophrenia
Case Report

January 8, 2026

A 42-year-old woman with schizophrenia and multiple prior hospitalizations presented with worsening psychosis and physical aggression toward her mother.
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PCC
Kratom-Induced Psychosis
Letter to the Editor

January 8, 2026

The author comments on the complexity of substance-induced presentations, particularly those related to newly available psychoactive substances such as kratom.
PCC
Family Support for Patients With Substance Use Disorders
Original Research

January 6, 2026

Family inclusion in SUD treatment improves patient outcomes, but provider referrals remain limited; health care providers should prioritize connecting patients with available family support resources.
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PCC
Semaglutide for Alcohol Use Disorder
Letter to the Editor

January 1, 2026

The authors explore potential mechanisms underlying the relationship between GLP-1 agonists and AUD as well as studies evaluating semaglutide for AUD.
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PCC
Transient Loss of Consciousness in an Adolescent with Pathological Intoxication
Case Report

January 1, 2026

This case of atypical symptoms in a 15-year-old boy underscores the need to differentiate pathological intoxication from seizures and psychiatric conditions, emphasizing alcohol abstinence.
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PCC
Machine Madness: A Case of Artificial Intelligence Psychosis
Case Report

December 30, 2025

A 41-year-old man with a history of substance-induced psychosis, developed symptoms of psychosis related to frequent occupational use of AI.
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PCC
A Case of Kratom Withdrawal
Case Report

December 25, 2025

A 29-year-old man experienced kratom withdrawal that necessitated intensive care management and resulted in subsequent cardiac arrest.
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PCC
Diagnosis and Management of Rage
Rounds in the General Hospital

December 23, 2025

This article offers a practical framework for distinguishing rage from irritability and impulsivity, identifying underlying neuropsychiatric drivers, and guiding evidence-based management across conditions including PTSD, TBI, and mood disorders.
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PCC
Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration
Case Report

December 18, 2025

The author presents a case of clozapine-induced QTc prolongation and discusses its relationship with serum clozapine concentration
PCC
Balancing Pragmatism and Ethics in Psychiatry
Case Report

December 16, 2025

A psychiatrist strategically used a patient’s internalized fear of extremism to redirect behavior during a manic episode.

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