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Care Companionfor CNS Disorders

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PCC
Antidepressant Monitoring Referrals to Higher-Level Services
Original Research

Antidepressant Monitoring Referrals to Higher-Level Services

April 23, 2026

This study examined predictors of referral from a collaborative care model antidepressant monitoring program to higher levels of psychiatric services.
, , , et al
PCC
Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome
Case Report

Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.
, , , et al
PCC
Alcohol Craving and Mood Disorders
Original Research

Alcohol Craving and Mood Disorders

April 21, 2026

Craving and alcohol-related severity differ between major depressive disorder and bipolar disorder even during euthymia, so accurate diagnosis is crucial.
,
PCC
Osmotic Demyelination Syndrome Presenting as EPS
Case Report

Osmotic Demyelination Syndrome Presenting as EPS

April 21, 2026

A 44-year-old woman was initially referred for presumed domperidone-induced extrapyramidal symptoms, but further workup uncovered a complex interplay of hyponatremia, demyelination, and neuroleptic hypersensitivity.
, , , et al
PCC
Cultural Manifestations of Bereavement in a Chinese American Patient
Case Report

Cultural Manifestations of Bereavement in a Chinese American Patient

April 16, 2026

The authors highlight the difficulties of applying western psychiatric concepts to cultural minorities, as seen in a case of complicated bereavement in a 54-year-old Chinese American woman.
, , , et al
PCC
7-OH-Mitragynine–Induced Psychosis
Case Report

7-OH-Mitragynine–Induced Psychosis

April 14, 2026

The authors present the case of a patient who developed psychosis and delirium following several months of heavy 7-OH use that persisted for nearly a week following cessation.
, ,
PCC
Acitretin, Homocysteine, and Neuropsychiatric Symptoms
Case Report

Acitretin, Homocysteine, and Neuropsychiatric Symptoms

April 14, 2026

This report describes a case of acitretin-associated hyperhomocysteinemia that induced neuropsychiatric symptoms in a patient with chronic plaque psoriasis, highlighting the need for monitoring.
, , , et al
PCC
Dose-Dependent Valproic Acid–Induced Hyperkalemia
Case Report

Dose-Dependent Valproic Acid–Induced Hyperkalemia

April 9, 2026

The authors present the case of a young man with bradycardia and Jacobs syndrome, in which a clear, dose-dependent relationship between valproic acid and hyperkalemia was observed.
,
PCC
How to Document Complex Cases
Rounds in the General Hospital

How to Document Complex Cases

April 9, 2026

Case presentations often drive differential diagnosis creation by what is said (and not said) and by whether information given is the “lead” or merely a (potentially interesting) tidbit.
, , , et al
PCC
Succinylcholine Misuse in a Health Care Worker
Case Report

Succinylcholine Misuse in a Health Care Worker

April 7, 2026

A health care worker with a history of PTSD and substance use misused succinylcholine for stress relief and sleep, highlighting the risks of occupational access to high-risk medications among…
, , , et al
PCC
Managing FND and Psychiatric Illness
Case Report

Managing FND and Psychiatric Illness

April 7, 2026

This case of a 54-year-old woman with schizoaffective disorder illustrates how stigma around psychiatric conditions can impact patient disposition, particularly in patient populations with complex neurological disorders.
, , , et al
PCC
Bupropion-Dextromethorphan for Clinically Challenging Apathy
Case Report

Bupropion-Dextromethorphan for Clinically Challenging Apathy

April 2, 2026

This case shows potential benefits of glutamate system–activating medication in addressing clinically challenging apathy in a 44-year-old man with depression.
, , , et al

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