Original Research

Recently published articles about Original Research

JCP
Psychiatric Hospitalization and Suicide Attempts in Healthcare Professionals
Original Research

December 31, 2025

Daily suicidal ideation and severe sleep disturbances were found to synergistically elevate suicide risk among healthcare professionals.
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JCP
Valproic Acid Use in Females of Reproductive Age
Original Research

December 15, 2025

Approximately 1 in 5 valproic acid (VPA) prescriptions between 2017 to 2022 were prescribed to females of reproductive age. Only 14% of females of reproductive age using VPA were...
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JCP
Obstetric Outcomes of Oral Versus Long-Acting Antipsychotics
Original Research

December 10, 2025

Similar rates of gestational diabetes, eclampsia, preeclampsia, and maternal hypertensive disorders were observed with long-acting injectable and oral second-generation antipsychotics.
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JCP
HIV Diagnosis and PrEP Prescription in Commercially Insured Persons with Bipolar Disorder
Original Research

December 8, 2025

PrEP use among commercially insured people with bipolar disorder was critically low, with fewer than 1% prescribed PrEP.
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JCP
Suicidality in Postpartum Women with Unipolar and Bipolar Depression
Original Research

December 3, 2025

The Edinburgh Postnatal Depression Scale does not consistently detect suicidality in perinatal bipolar patients. Only slight agreement with clinical assessment was seen for this high-risk group.
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JCP
Lack of Generalizability of PTSD Treatment Trials: The Recent Brexpiprazole-Sertraline Trials as an Example
Original Research

November 26, 2025

In an outpatient psychiatry sample, nearly 95% of patients who want treatment for PTSD would not have qualified for the trials of brexpiprazole-sertraline for PTSD.
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Recent JCP Articles on Original Research

JCP
Rechallenge of Lamotrigine After Rash: A Systematic Review
Systematic Review

December 31, 2025

Lamotrigine has been rechallenged safely in select cases, but it is critical to confirm that the initial rash did not have specific features of a severe rash in order...
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JCP
Dr Michael Asbach on the Evolution of PAs in Psychiatry
Podcast

December 30, 2025

Physician Assistant Dr. Michael Asbach addresses workforce solutions in psychiatry, from PA training and autonomous collaboration models to recent UK policy debates. Learn how interdisciplinary teams can expand access,...
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JCP
Precision Medicine for Suicide Prevention: It’s Time to Take the Next Step
Commentary

December 22, 2025

The authors recommend moving toward a precision medicine approach to suicide prevention that considers the person, their circumstances and biology, treatment delivery context, and conditions that contribute to the...
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Recent PCC Articles on Original Research

PCC
Semaglutide for Alcohol Use Disorder
Letter to the Editor

January 1, 2026

The authors explore potential mechanisms underlying the relationship between GLP-1 agonists and AUD as well as studies evaluating semaglutide for AUD.
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PCC
Transient Loss of Consciousness in an Adolescent with Pathological Intoxication
Case Report

January 1, 2026

This case of atypical symptoms in a 15-year-old boy underscores the need to differentiate pathological intoxication from seizures and psychiatric conditions, emphasizing alcohol abstinence.
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PCC
Machine Madness: A Case of Artificial Intelligence Psychosis
Case Report

December 30, 2025

A 41-year-old man with a history of substance-induced psychosis, developed symptoms of psychosis related to frequent occupational use of AI.
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Featured Original Research Research

Researchers Reverse Alzheimer’s Damage. At Least in Mice.
news

December 31, 2025

A new study shows that restoring brain energy metabolism can reverse advanced Alzheimer’s-like disease in mice.
First Targeted ALS Drug Shows It Can Change the Disease
news

December 30, 2025

Early, sustained treatment with tofersen significantly slowed disease progression, stabilized function, and extended survival in patients with SOD1-related ALS.
Could Swearing Be Good For Us?
news

December 29, 2025

A new study suggests that swearing at the right moment can modestly but reliably boost physical performance.

Consensus Report on XT Use in Practice

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