Original Research
Recently published articles about Original Research
Original Research
Mental Health Impact of COVID-19 Pandemic on the Mental Health of Middle-Aged and Older Adults: A Cross-sectional, Comparative Study
September 11, 2025
Older adults were found to have less depression and anxiety compared to middle-aged adults; loneliness and perception of knowledge about COVID can affect the association between the presence of...
Original Research
Validity of an Online ADHD Assessment in a Real-World Sample of Adults Seeking Web-Based Mental Healthcare
September 8, 2025
The online assessment correctly identified over 80% of ADHD-positive cases. Compared with the clinical interview, the online assessment was more conservative in rendering ADHD-positive diagnoses.
Original Research
Effects of the October 7, 2023, Terrorist Attack on PTSD, Depression, Anxiety, and Suicidal Ideation Across Distinct Exposure Groups
September 3, 2025
Prevalence and severity of psychiatric symptoms declined between 1 month and 1 year following the attack; exposure group moderated these changes. Reserve-duty combatants had the highest rates of probable...
Original Research
Comparing the Cognitive Effects of Repeated IV Ketamine and ECT in Patients with Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial
September 3, 2025
Patients treated with ketamine demonstrated superior cognitive functioning compared with those treated with ECT following a 3-week treatment course. No differences between treatments were observed among responders in at...
Recent JCP Articles on Original Research
Clinical and Practical Psychopharmacology
Ketamine-Associated Uropathy During Therapeutic and Nontherapeutic Use
September 10, 2025
Higher doses, more frequent dosing, longer treatment duration, and oral administration are potential risk factors for ketamine-associated uropathy in maintenance therapy.
Commentary
Practitioners Providing Care for Persons with Severe Mental Disorders Should Routinely Screen for Metabolic Dysfunction–Associated Steatotic Liver Disease
September 10, 2025
Persons with severe mental illnesses should be routinely screened for MASLD as part of a psychiatric and medical assessment that includes social and economic determinants of health, risk factors...
Insights
It Takes Guts to Be Mentally Ill, Part 1: A Brief Overview of the Human Gut Microbiota
September 8, 2025
Dr. Henry Nasrallah introduces the human gut microbiota and its role in brain health, highlighting how early life, diet, antibiotics, and lifestyle impact microbial balance — and how gut...